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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ccd3efa5e97af5fd9bb1c5581b3ef15a33832e187f2ee41af52d96c7d49f200' 
  AND token = 'eEUFgCVS7TapHNoBIgBrV+qR+9pgoBoCa4Y81ZwYOm8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}