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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a8b0663fc8ed39acf24ed2b12f802a8729b6078b0d2e75f4646a5a333a581c0' 
  AND token = 'wXg7w3DHit06a755IqBR/F0MLNS5ul0C1Wmc0cAzv3A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}