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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ce22e3ab3ec8673d60ff40bc2227cff4e63f0ec34539567a320196b4b1c3a06' 
  AND token = 'MP8teYv81/0NRJ2hm1w0VsQAxUiwlqG0GoUT0DHUDJg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}