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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73ab7a89aa364ecff5ab4be535743e309c84fca9e17e50faa753a904eef46915' 
  AND token = 'I7IcIDMoT0sDW/DJIPm+W5Sck4pmJbEwSldUF6OB/iY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}