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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46ac4bdbec4cbd11a69ea9125fd4e173b993a0d50324e1608b046736503126c0' 
  AND token = 'k2H617Oa68WY++Zn+FsrOyO1kKmmlk2HUvktUd9AjSw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}