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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '266a695be204f9b630d6077784a52e0b9fb280e280f841d2da81986c3979783b' 
  AND token = 'AWeE/X7xu61IAAPjN8bpuYSIaSt6CM2Wxx0ox6oMZ+I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}