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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8fecf8aa0152172899577e3b748d3983b7d3742ddddf21da3b06df063c270132' 
  AND token = 'zTVoQ5ZAvnF5JmbbViJl4tSs0Q4Ng+HSHsDZD29FaC0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}