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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6791c92875b94eb3f0d056ed1497c6b4f64574ff579f99cb3a16a0b14548fe48' 
  AND token = 'gtTwMEJhpYXVXQeFCu+KJrCoxQ9g1qeJbQdpMxO1bxQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}