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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50a0bbdd4c11df230533b9682b0ce786a06628cce4835deb10cf03b795775483' 
  AND token = 'qmud4e1x69Bf30c7t8v0Jzp99K9Q/ejcJZw0sH7lF+M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}