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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a48cf538687c6c05ab3065f6d0784480da4edeb74bbe37400dbeeebc0d929c15' 
  AND token = 'IYzf2ZxoRbIMrt08TjcEaipKeXBsMMya4yyQgeuKE0g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}