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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd75432cf084d44e9180e5c354769eb8ba456189b4df0e535afe2d0081e4afaad' 
  AND token = 'UZVU3p5jj3UE3b3LuzfpWXrxzNuqa9UllZcuHVinzYA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}