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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ede20da2e769f27d4da2165bc034bfe359454f33fb579dd78b6e883e5e1e1eee' 
  AND token = 'tJWtplGxaQ1FGUvCyYiLjcgihfKZ1jfTemYKgQCG4I8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}