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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6255085b69e16aad64e4e49b541f41b4abc86f937b756d73c710cffcb60f4963' 
  AND token = 'MD5nShEFSWA45lbIdAZg59R7NznYYSoThxvYWKWL5zM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}