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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0d5746100a46b465be2c9dc563576ed166b505079a340b96df04475f53373a1' 
  AND token = 'DkGAxE9lzBXWL/7SH+7l2inLv+4YIZeMMu7JFP93r2k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}