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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6c1b6e96cc755b82b27c08518808e18451244777cfd50a202cff07cd727e38d' 
  AND token = 'yMFSbc14Mw0qDjpgM+iFl56ZWd3fb73S5y/Z31CpX+k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}