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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0fff601c7d87a4d3a2e99bcf880107a1a4c8763681fa9aa81bcf8ed43448f10c' 
  AND token = 'HVYfpSQuSeKUM1loN4eNkpaRhr/ZHFOB+EpYygVBTxw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}