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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10f79aa95276232e5358e5b3d9c939bfa6af9b7a5ccb6fe39aa10b6891839091' 
  AND token = '4mfsrFHZU79Ju/Sx8hp3TcoR7QemHvuOd2F1AwfMt0c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}