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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fbef160ca3f6dcc0c8909da381d0bbe645ae9778a505484492f44c54ff2f0fe8' 
  AND token = 'fzX1Ly4kJh2XjJyNxd9wqWW/+5ATmY07Q+MymBOG+8s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}