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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5bf89587e31e63a514e0006cdacf641d57a8feef40a64446e9e9f3972359dafb' 
  AND token = 'IeTzm2U7yuCN+bfEx0cC77lwOfHNwz2enXolNXG73Fo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}