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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bd4cc1e1c5aac104e18cf247501abe06ef1950b1519bf43710da91b90a983d0f' 
  AND token = '6nBSVuQt3sK4c0FKGP0uwXhanQRX2+1E76JFyhp90p4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}