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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22e8141dc52fa7070fd5de3ae1fecbeb3aaf693739b31ba1baac3fbab699b765' 
  AND token = 'e+OTrIGUZAes+ql0Zvs4KZXciSsM+kGpojF2J/cwnio=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}