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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9eaca2884f6ae2d1ec3c51b851be21ccaaeade4f74061f6405e97df8a607601a' 
  AND token = '9UJrUOxsaLtkRBr/k4F5CjF5VyA0WNQJsYdbkWOj8wM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}