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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66acba532346d16bd738e3f1efcafa253b244d1f093091d4d8155e07d7c812b5' 
  AND token = 'jsLigkFS12E6NF7BLoujS3cgLYzkzLe4BGXmZsPKM04=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}