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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2c46cf374b2950e0984967e1ce324819a96124de5bd6d4772de20966fa1b866' 
  AND token = 'SXCvPOs7tid0kPIprIDrUzKdKdkgn1JIulUs2oZnics=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}