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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ee05a81e52d5100b73846b1ecbffaca57c043c29fdaefeb7a00ff35e7cd329d' 
  AND token = 'ePle7gV4gjOq01TAkyhSX1O5X+IZ+aiEX6NF0JdmVs8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}