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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a2569a4a860e1ce3fdb32f1a958f17198ac33b429d9ef8aa73a75295c698430' 
  AND token = 'mkI6nPR8EWPIIxsjH087tjFJZ3NSmAFoOXccz+mq5J0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}