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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bf25130c45a37651a8bdbf3b3387e41ee9dce234343844abac7c17e195dc6ac1' 
  AND token = 'FI3Tw+WTiqVIyl93mJg7uU742Q6D0l0lw4JjsevzHPU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}