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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5730caf51c09d19c775f29e9f5abdfca843dfd4292d657ee7babed09b40d5c3' 
  AND token = '+jv4oe1ZrNI3vvOrF4aGJwdFZRSYuwkjX3IQPNfzDMg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}