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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b89c4cc6cf4f377b636f9d637b8a9e611179c8dac3b50c70b15462bcadbf6147' 
  AND token = 'ghYKB3GprStcabPSeX3gzK/Qo+sfa1MWhuy5lELhwHE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}