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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50eb93d38cdfd85110ff3a91ff30b7329123e0129d75928f2e48b7d70b0994bb' 
  AND token = '4GuZOn/Br0nFUXe41VmsbpaPczwiHACz8AJAdhAdi8o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}