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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '753150f782560fae942a9e6e175854d5dce6210e51293111e8351da6a7296ae9' 
  AND token = 'IxsGYPyqA76mELjOMe6mjWEaPD+hoflhjJnAmat93nE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}