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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '824585c15cbb7793f8f62c27da0e012816448075fd2cb0c15aa2ecc985dcbe03' 
  AND token = 'UINoWw72ZDd01NGnCVOzvTeMjL6IHHj9TYklAMYD3i4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}