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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd816f9700cce7a5a886f27c2a18c71be8482328c04b1da033c5f9820e0628218' 
  AND token = '+4aTwFGSNVr5mq6jKEb+5wuTMsHXV17buIWjHYQhRMc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}