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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e75a2117ed5ceba7d509afbcc4f642e0d5f88901df69e36b359fc5fb5579726a' 
  AND token = 'uQeOxFCrRmY0I8w37PeNXW2qSJQm3d+ZyZUSHYgdX+A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}