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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f472766869a03d10eab33806e3b6b7360c95a8ccb9c4ddfa736ac0de86355f58' 
  AND token = 'OWsy5nH0IuA7EeIxDPZvEI+y/f2xVXnYbLqQdhNxivI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}