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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4955fec360fe7f991fa7be6f42a41c67c542750ee5a20491464e144332562898' 
  AND token = '5kDdg4IRRmn+tYK7weQxtZ+M6GNI1OLF4SJGSlHqgNw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}