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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06274a8e4a5c071b830ce678255197d8307f2f8bfd80271da2dfc05702c8d358' 
  AND token = '8e4tJZ5iOQMmkKxZWyLMB4vqKxzQxq8VvmitRq3vf7E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}