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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6a5002890260ab1a353eb1697ce2425bf88179faf93cf1fe6ddef25421c0598' 
  AND token = 'aU0D+t5hLWQAxRP4k+QXIKghPIFZXH3PFisWVZ1k7NU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}