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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6921e7b4bc76a31dff715f43a2fd3bee0e48d30a0e853afe72cb290d9a1a147b' 
  AND token = 'Si1nhMDly9PrlOFcgT3HwERXjGxjc/1evLbAB2SndFA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}