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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25f58a677b04596a4f4736e80c3150e090d109b22ed8ab78c4509967d8fd947a' 
  AND token = 'jHvD1azqZCUKrSz+ANQdP1QD5EA6t6hkACbUWiaaPYE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}