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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c176a0721dd5f037046b15b8f651c422b1d1950876236b14c27d593bea39971' 
  AND token = 'mYWbCikJujN/RA2zS2VGHi6lbk1jmnSQuzZdyiX01jE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}