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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e82f873319e7d8f97d1fef2880f77da4982efaa7a6520a4fa06f7ec14b35256' 
  AND token = 'ASg8MYBh8hpP5MynKrJlvm4PEsmdM2xm0mkjpFkS6Ms=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}