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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5efbb0224da010fdafda131b5f13db5f0a240069aefe00923df0ccc59e058744' 
  AND token = 'gIUy4xJM+Wl72eBM7Oup2/m2/o6W1Oj1tZ5tyfM7Lm4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}