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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45fa71f3e0251df523e4bd3245fa57eeacf205871d0dbf8c299d8b370371752d' 
  AND token = 'qUzPFfQ+ScLLcY4DDj3Rxu6LVeilik0pAk5odqSgnW8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}