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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e793df66e09c222c7b55f13b4e14ac705200549f902db4839c99e23c2cf068f4' 
  AND token = 'sUqeVepLy2RHbWrZsXIN2EQlvOOumHjITYXuXXjj0Bg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}