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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4084e04b96993be70cd4a1d0915bb8d6420173f5d739b91e53f57327a747f94' 
  AND token = 'Mu+yJqcS/DAlcOZ1AFMR2O/RA4UHXiLSOjx8daYmOMM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}