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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7324860827d756292a0cf7c51f82bb7d921deb06a237bafb20368101d7406f0' 
  AND token = 'i+1qnh0R6V+AjrgDW2qKDWb95PsIpShsaR7D6XZW1zQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}