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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88ff2794b770a1ddbc1e19ad8fe2a5235cf9bb5f2ce32322209e27d39b146fbc' 
  AND token = 'XkVMDc1094j67JzD9dkMdAULMVlyVe1qJDuAY0uZ2Gs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}