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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18151c7d4d2b2c06d4e754fd4eca18e47b737108d00801642078847f2c3725df' 
  AND token = 'jA3Zf57btXjbr7oZ24bFVTQkY8xgAreTA4SwJvEN9w8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}