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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c33b451a530d6649e7f5443d8a13ccfbb18cb46231a754e03c089116a622b19' 
  AND token = 'ZwfiIMxedKtsfWqktUM/aX1LinkraV8dykqJLwyhtA4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}